Denmotoxin: a Three-finger Toxin from Colubrid Snake Boiga Dendrophila (mangrove Catsnake) with Bird-specific Activity
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چکیده
From the: ‡Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore 117543; §School of Biological Sciences, University of Northern Colorado, 501 20th St., CB 92, Greeley, CO 80639-0017, USA, ¶Current address: Australian Venom Research Unit, School of Medicine, University of Melbourne, Parkville, Victoria 3010, Australia; ║Department of Pharmacology, Faculty of Medicine, National University of Singapore, Singapore 117543; †Département d’Ingénierie et d’Etudes des Protéines, Commissariat à l’Energie Atomique, Gif-sur-Yvette Cedex 91191, France; #Department of Biochemistry and Molecular Biophysics, Medical College of Virginia, Virginia Commonwealth University, Richmond VA 23298, USA
منابع مشابه
Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.
Boiga dendrophila (mangrove catsnake) is a colubrid snake that lives in Southeast Asian lowland rainforests and mangrove swamps and that preys primarily on birds. We have isolated, purified, and sequenced a novel toxin from its venom, which we named denmotoxin. It is a monomeric polypeptide of 77 amino acid residues with five disulfide bridges. In organ bath experiments, it displayed potent pos...
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تاریخ انتشار 2006